Boehringer Ingelheim Scientist II/III, Bioanalytical Mass Spectrometry Group, DMPK in RIDGEFIELD, Connecticut

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment which benefits our employees, patients and communities.

Candidate will be hired at level commensurate with experience

Description:

Boehringer Ingelheim is seeking an enthusiastic, creative and highly motivated BioanalyticalScientist II/III to join the Bioanalytical Mass Spectrometry (BAMS) group in Drug Metabolism & Pharmacokinetics (DMPK) at our US headquarters in Ridgefield, CT. The BAMS Group is a technical leader in the field of bioanalysis of protein drugs following proteolytic by LCMS using surrogate peptides (PrD-LCMS). We are currently engaged in developing, validating and applying state-of-the-art bioanalytical methods for nonclinical and clinical studies of small molecule and protein drugs using LCMS instruments.

The main responsibilities of this position include: method development, validation and troubleshooting of GLP/GCP bioanalytical LCMS methods; investigation and implementation of new technologies and training/mentoring of junior scientists. In addition, performance of work must be in conformance with applicable regulations and in a safe manner. The successful candidate for this position should have a strong background in GLP/GCP small molecule LCMS bioanalysis. Additional experiences and knowledge in LCMS bioanalysis of protein drugs via surrogate peptides following proteolytic digestion and/or immunoassays is a plus.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities:

  • Design and executenon-GLP, non-GCP method development experiments and sample analysis using LCMSwith minimum supervision. Perform routine procedures independently andnon-routine procedures with some supervision.

  • Assume GLP and GCPbioanalytical responsibility for development drug candidates under supervision.This encompasses bioanalytical development, method validation, sample analysis,reporting bioanalytical data and responding to auditing by QA and FDA. Theseskills apply to both small molecule LCMS bioanalysis and LCMS bioanalysis ofproteins using both direct digestion and immunocapture techniques.

  • Perform all work inconformance with applicable regulations (GCP practices, 21 CFR Part 58, andSOPs) and perform all work in a safe manner.

  • Effectivelycommunicate and defend own work at internal meetings, orally and in writing, inthe context of the team goals.

  • Perform data analysis and report writing with a highlevel of integrity and ethics.

  • Participate in cross departmental project teams whenassigned.

  • Propose, gainsupport for and implement ideas from individual's knowledge of science andtechnology and understanding of drug discovery/development process.

  • Propose, evaluate,and implement new technologies; independently apply basic scientificprinciples, perform literature searches, attend scientific meetings, and keepabreast of literature in own field and in regulatory aspects of GLPs and GCPs,particularly for the bioanalytical disciplines.

  • Demonstrate a solidlevel of technical proficiency and trains technicians/junior scientists asappropriate. Keep up-to-date knowledge on applicable regulatory guidelinesrelating to small molecules and proteins by LCMS.

Scientist II Requirements:

  • Master’s Degree with 0 - 2 years’ experience orBachelor’s Degree with 3+ years’ experience in related scientificdiscipline, with education background in chemistry, biochemistry orbiology.

  • Pharmaceutical, biotechnology or CRO experience ishighly desirable.

  • Experiencein developing, troubleshooting, and validating LCMS bioanalytical methods. Experiencein LCMS protein assay and immunoassay is a plus.

  • Experience working in a GLP/GCPenvironment.

  • Proven problem solving ability.

  • Ability to operate and maintain laboratory equipmentwith some supervision.

  • Excellent written and verbal communication skills andability to draft technical reports.

  • Proficiency with computers and data analysis software.

  • Ability and willingness to work effectively in a highlycollaborative environment.

Scientist III Requirements:

  • Master’s Degree with 3+ years’ experience or Bachelor’sDegree with 7+ years’ experience in related scientific discipline, witheducation background in chemistry, biochemistry or biology.

  • Pharmaceutical, Biotechnology Company or CRO experienceis highly desirable.

  • Proficient in developing, troubleshooting, andvalidating (according to regulatory requirements) LCMS bioanalytical assaymethods; experience in LCMS protein assay and immunoassay is a plus.

  • Experience working in a GLP/GCP environment is highlydesirable.

  • Experience in the use of laboratory automationequipment is highly desirable.

  • Proven problem solving ability.

  • Ability to operate and maintain laboratory equipmentwith independence.

  • Excellent written and verbal communication skills andability to draft technical reports.

  • Proficiency with computers and data analysis software.

  • Ability and willingness to work effectively in a highlycollaborative environment.

Eligibility Requirements:

  • Must be legally authorized to work in the United Stateswithout restriction.

  • Must be willing to submit to a backgroundinvestigation, including verification of your past employment, criminalhistory, and educational background

  • Must be 18 years of age or older

Our Culture:

Boehringer Ingelheim is one of the world’s top 20 pharmaceutical companies and operates globally with approximately 50,000 employees. Since our founding in 1885, the company has remained family-owned and today we are committed to creating value through innovation in three business areas including human pharmaceuticals, animal health and biopharmaceutical contract manufacturing. Since we are privately held, we have the ability to take an innovative, long-term view. Our focus is on scientific discoveries and the introduction of truly novel medicines that improve lives and provide valuable services and support to patients and their families. Employees are challenged to take initiative and achieve outstanding results. Ultimately, our culture and drive allows us to maintain one of the highest levels of excellence in our industry. We are also deeply committed to our communities and our employees create and engage in programs that strengthen the neighbourhoods where we live and work. Boehringer Ingelheim, including Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Animal Health USA, Inc., Merial Barceloneta, LLC and Boehringer Ingelheim Fremont, Inc. is an equal opportunity and affirmative action employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender identity or expression; affectional or sexual orientation; disability; veteran or military status, including protected veteran status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

Boehringer Ingelheim is firmly committed to ensuring a safe, healthy, productive and efficient work environment for our employees, partners and customers. As part of that commitment, Boehringer Ingelheim conducts pre-employment verifications and drug screenings.

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Organization: US-BI Pharma/BI USA

Title: Scientist II/III, Bioanalytical Mass Spectrometry Group, DMPK

Location: Americas-United States-CT-Ridgefield

Requisition ID: 184118